About 1 in patients get the severe form of OHSS. When choosing your clinic, ask them about their OHSS management. The condition must be taken seriously. And it usually is. Your comment. Email [email protected]. Call us on Scan once, twice or more. Get the meds right. Coast it. If in doubt, delay. Follow Us Facebook. Sitemap Website Terms of Use. Spread the word! More information about our Cookie Policy. Egg Donation. Blog Patient Center Educational Videos. What is Infertility? Preconception Health and Well-being.
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Instead of the standard dose of 10, units, one may lower the dose to 5, or even 3, This may reduce the number of mature eggs retrieved, but will also reduce the incidence of OHSS. In the meanwhile, the larger follicles will continue to grow and the smaller follicles which contribute to OHSS do not.
Antagonist coast. In patients who are down regulated with Lupron, one can stop the Lupron and give a GnRH antagonist Ganirelix, Cetrotide for a couple of days while continuing the fertility drugs at a low dose 75 units hMG daily s.
This results in a prompt drop in the estrogen levels probably due to direct action of the GnRH antagonist on the granulosa cells and VEGF production. Agonist trigger. The use of 40 units of Lupron has been suggested as being adequate.
The details of this approach will be discussed in a subsequent blog. It can also be combined with a low-dose hCG trigger 1, — 1, units given at the same time or just after egg retrieval. Use of dopamine agonists. Cabergoline is a drug that has been used for treatment of elevated prolactin levels for many years. Cabergoline 0. Freezing all the eggs or embryos. Since pregnancy will increase the severity of OHSS, it is often prudent to postpone embryo transfer to a subsequent cycle in patients that are at high risk for OHSS.
Early tapping of the ascitic fluid.
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