There have only been a few reported cases of priapism with the use of phosphodiesterase type 5 inhibitors, used to treat erectile dysfunction 3. Priapism has also been associated with methylphenidate treatment, both with dose increases and decreases 4. The Medicines Adverse Reactions Committee recently considered this association and noted the possibility of more than one biological mechanism. This may be demonstrated by reports of priapism associated with both increase in dose and methylphenidate withdrawal.
Sickle-cell disease, or anemia, is closely linked with the development of priapism. Some studies show that nearly half of men with sickle-cell disease will eventually develop this condition. Certain medications are also linked with this condition — particularly Thorazine and Desyrel, used in the treatment of depression and other mental conditions. If you are being treated for ED, some of the medication used to treat your condition could cause priapism. If you have an erection lasting for several hours, regardless of whether it is painful, you should seek medical attention at an emergency or urgent care facility.
The blood trapped in the penis becomes starved of oxygen, and can cause permanent disfigurement of your penis or Erectile Dysfunction. Do not attempt to treat this condition yourself. Paraplegia ; 7 : — CAS Google Scholar. Spinal cord injury. In: Stover E et al. De Le Torre J. Review of basic and applied research.
Spine ; 6 : — Toscano J. Prevention of neurological deterioration before admission to a spinal cord injury unit. Paraplegia ; 26 : — Missed and mismanaged injuries of the spinal cord. Trauma ; 53 : — Download references. You can also search for this author in PubMed Google Scholar. Correspondence to N V Todd. Reprints and Permissions. Todd, N. Priapism in acute spinal cord injury. Spinal Cord 49, — Download citation. Received : 02 September Revised : 07 April Accepted : 17 April Published : 07 June Issue Date : October Anyone you share the following link with will be able to read this content:.
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Skip to main content Thank you for visiting nature. Download PDF. Subjects Spinal cord injury Urogenital diseases. Abstract Study design: Prospective literature review; search via Oldmedline — , Medline — and Pubmed. Objectives: The objective of this study is to review the pathophysiology of priapism in acute traumatic spinal cord injury SCI ; to determine the incidence of priapism in traumatic SCI, whether or not priapism is associated with incomplete or only complete SCI and whether and what treatment might be required.
Methods: This is a review article based upon the available literature in this area. Results and conclusions: Priapism that follows acute traumatic SCI is high-flow non-ischaemic priapism, that is, the blood within the corpus is arterial in nature.
Introduction Priapism is persistent erection of the penis. Methods A literature search was performed on Oldmedline — , Medline — and Pubmed. Results There is a very restricted literature that has reported priapism in patients with SCI. Discussion Classification of priapism Priapism has been subdivided into two types: 1 low-flow ischaemic or 2 high-flow non-ischaemic. Evidence from judicial hanging Following judicial hanging in men, there may be a complete or partial erection with or without ejaculation the terminal or death erection.
Medicolegal implications There are implications, medicolegally, in determining the timing and causation of SCI. Conclusions Priapism occurs in a proportion of men with acute traumatic SCI. Google Scholar 22 Vermooten V.
Article Google Scholar 36 Toscano J. Article Google Scholar Download references. Ethics declarations Competing interests The author declares no conflict of interest. If you experience recurrent, persistent, painful erections that resolve on their own, see your doctor.
You might need treatment to prevent further episodes. An erection normally occurs in response to physical or psychological stimulation. This stimulation causes certain smooth muscles to relax, increasing blood flow to spongy tissues in the penis. As a result, the blood-filled penis becomes erect. After stimulation ends, the blood flows out and the penis returns to its nonrigid flaccid state. Priapism occurs when some part of this system — the blood, vessels, smooth muscles or nerves — changes normal blood flow, and an erection persists.
The underlying cause of priapism often can't be determined, but several conditions may play a role. Blood-related diseases might contribute to priapism — usually ischemic priapism, when blood isn't able to flow out of the penis.
These disorders include:. A common cause of nonischemic priapism is trauma or injury to your penis, pelvis, or the region between the base of the penis and the anus perineum.
Ischemic priapism can cause serious complications. The blood trapped in the penis is deprived of oxygen. When an erection lasts for too long — usually more than four hours — this lack of oxygen can begin to damage or destroy tissues in the penis. Untreated priapism can cause erectile dysfunction. Mayo Clinic does not endorse companies or products.
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